Dr. Gary’s Nutritional Library

Andrographolide is a chemical called a diterpine lactone found in the plant called Andrographis paniculata. This plant has been shown, scientifically, to have anti-inflammatory activity, which is an oriental traditional medicine used to treat inflammation. Injections of derivatives of andrographolide, called Lianbizhi, have been found to inhibit gastric, liver and lung cancers in living patients.

The present study was done to test the anti-cancer effects of andrographolide in the laboratory against several cancer cell lines. Prostate cancer cell growth was inhibited the most and had the most apoptosis, demonstrated by cellular and DNA analysis. The inhibition of cell proliferation was equal to that of cisplatin, a pharmaceutical chemotherapy medication.

Vascular endothelial growth factor (VEGF) is a chemical important in the growth of cancers. Its presence is important in the prognosis of cancer cells since it promotes the growth of new blood vessels (angiogenesis) supplying nutrition and oxygen to tumors. Andrographilide was shown to have a marked inhibitory effect on VEGF release in prostate cancer cells (PC-3 type).

CONCLUSION: Andrographolide, from Andrographis paniculata, is a chemical that has anti-inflammatory activity and has been shown by this study to be effective against several cancer cell lines. It was most effective against a type of prostate cancer cells in which it induced apoptosis and inhibited VEGF.

NOTE: Apoptosis is a programmed type of cell death that has been found to be effective against cancer cells. VEGF is a chemical produced in cancers to cause the growth of new blood vessels, angiogenesis, a process required for cancers to grow. Blocking angiogenesis is another new way to treat cancers. Read about the effect of Andrographis in vascular and tumor biology.

Summary 153 is a review of anti-oxidant studies of Andrographis panniculata, an Ayurvedic herbal preparation known as Kalmegh. Diterpene lactones come from essential oils, gums or resins.

To read the author’s abstract of the article click on the link to the author’s title of the article above.

PMID: 18464090.

Summary #252.

Disclaimer

You are entering the portion of the website of Rainbow Grocery Cooperative, Inc., that is here “to strive to offer education”, as stated in our Mission Statement. Here we are reporting on scientific studies that are about the value of nutritional supplements and whole foods for our health. We will attempt to report on the latest studies regarding the supplements and foods sold at Rainbow Grocery. The summaries of the articles are our own. These summaries are not intended to promote any particular product or food that Rainbow sells, but only to provide information about them.

You are your own best doctor. Study as much as you can. Consult with your doctor. Find one open to alternatives if your doctor isn’t. Make your own decisions and take responsibility for your own health. We hope this information will help you make your decisions.

We can’t and don’t intend to prescribe for you. We can’t and don’t intend to provide medical advice. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Don’t disregard professional medical advice or delay in seeking it because of something you have read on this website.

Nothing in this website is intended to create a health practitioner-patient relationship. Reliance on the information provided on this website is solely at your own risk. In using this web site you agree that neither Rainbow Grocery Cooperative, Inc. nor any other party is or will be liable or otherwise responsible for any decision made or any action taken or any action not taken due to your use of any information presented at this web site.

Descargo de responsabilidad

Advertencia sobre el uso de los resúmenes de estudios médicos publicados en este portal:

Usted está entrando a la parte del portal de Internet de la Cooperativa de Rainbow Grocery, Inc. cuyo fin es “procurar ofrecer elementos educativos” tal como lo establece nuestra Declaración de Principios. Lo que aquí se reporta son estudios científicos sobre el valor nutricional de suplementos y alimentos completos para la salud. Trataremos de incluir los estudios más recientes sobre suplementos y productos alimenticios que se expenden en Rainbow Grocery. Los resúmenes de los artículos han sido elaborados por nosotros. Pero su inclusión no tiene como fin promover productos específicos que se venden en Rainbow, sino sólo proporcionar información sobre los mismos.

Usted es su mejor doctor. Estudie e infórmese tanto como le sea posible. Consulte a su médico. Busque uno de mente abierta a alternativas si el actual no lo es. Tome sus propias decisiones y hágase responsable de su salud. Esperamos que la información aquí presentada le ayude a tomar las mejores decisiones.

No podemos ni es nuestra intención ofrecer recetas o proporcionar asesoría médica. Usted siempre debe consultar con su médico u otro proveedor profesional de servicios de salud cuando tenga preguntas relacionadas con su salud. No ignore los consejos profesionales de su médico, ni deje de buscarlos en base a lo que haya leído en nuestro portal.

Nada en este portal tiene la finalidad de crear una relación paciente-profesional de la salud. El uso de la información aquí presentada es bajo su cuenta y riesgo. Al usar este portal, usted acepta que ni la Cooperativa de Rainbow Grocery, Inc. ni tercera partes son responsables de forma alguna por cualqui.